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张国捷  研究员
生物多样性基因组研究学科组
职  务:
学  历: 理学博士
电  话: +86 871 68125417
传  真:
电子邮件: zhangguojie@mail.kiz.ac.cn
通讯地址: 云南省昆明市盘龙区茨坝镇青松路21号    650203
其他主页: http://zhanggjlab.cn/en/pages/our_lab.html
  简  历

博士,研究员。现任哥本哈根大学生物系终身教授、中国国家基因库副主任、中国科学院昆明动物研究所生物多样性基因组学研究学科组负责人;生物多样性基因组学和生态演化基因组学领域专家。

张国捷教授于2010年在中国科学院昆明动物所取得博士学位后,赴丹麦哥本哈根大学(全球排名前50)社会行为演化研究中心作为访问学者。2012年受聘哥本哈根大学助理教授,2015年成为丹麦首个进入终身序列的助理教授,并于20173月获得终身副教授职位,同年9月被授予终身教授职位,成为哥本哈根大学建立500多年以来历史上首个华人正教授,同时也是目前哥本哈根大学最年轻的正教授。

在前沿生命科学领域——生物多样性基因组学和生态演化基因组学方面做出了引领国际的突出学术贡献。截至20198月,已在国际高影响力学术刊物发表论文120余篇,其中包括《Science14篇、《Nature8篇、《Nature Genetics6篇,《Cell》文章1篇,另有其他Nature子刊数十篇。其中近50篇以第一作者或通讯作者发表。多篇文章被选为封面文章,另有多篇受到《F1000》评选为重点推荐文章。文章总引用率超2万次,h-index 62i10-index 110。研究成果受到CNNBBC、纽约时报、华盛顿邮报、国家地理等主流媒体广泛报道。张国捷教授先后领导完成了多项国际重大动物基因组演化研究工作,研究范围覆盖了灵长类、哺乳类、两栖爬行类、鸟类、鱼类、昆虫和软体类等近百个生物演化过程中关键演化节点的物种,重点研究物种形成、物种极端环境适应、环境-生物互作、以及社会行为演化等演化生物学热点研究课题。首次提出利用全基因组数据重构物种生命之树,并解决了被誉为物种演化研究最困难的问题现代鸟类起源与演化关系。张国捷前后获得了多个国际奖励,被选为2017Nature Index封面人物。先后担任美国、加拿大、法国、瑞士、英国、丹麦、瑞典、以色列等多个国家基金会评委,常年担任NatureScienceCell在内的多个顶级国际期刊的稿件评审人,担任GigaScienceHuman HeredityZoological Research the Encyclopedia of Life Sciences期刊编委。

  研究方向

地球生命的物种组成、形态、及功能多样性形成的遗传机制是达尔文留给后人的未解之谜,是生命科学研究中最基础的学科之一。生物多样性基因组学是新近发展起来的新兴综合性学科,旨在利用比较基因组学、演化生物学、群体遗传学、发育生物学、生态学等多个学科的理论和技术交叉,系统回答生物形态功能的分子遗传基础、物种协同演化分子机制,以及生物演化与环境互作机制等重要基础问题。张国捷教授是国际上首批开展生物多样性基因组学研究的学者之一,也是这一领域最为活跃学者之一,并在多个方向取得了突破性研究成果:

1)建立大尺度比较基因组学研究体系,在国际上引领重构生命之树的研究;

2)通过比较基因组学解释物种的环境适应机制,丰富达尔文自然选择理论;

3)基于多学科交叉,创建发育生物学新范式,推动非模式生物特异性状发育和演化的分子机理;

4)建立研究社会行为演化及分子调控机制的新型动物模型,揭示基因调控和表观遗传调控对社会行为的影响。

目前在昆明动物研究所的团队主要以蚂蚁为模型,研究基因调控和表观遗传对社会行为的影响,从而解释社会行为的演化及其分子机理。为研究这一命题,张国捷教授与团队成员在基因组层面、表观调控层面以及神经生物学层面对蚂蚁社会等级及行为差异展开系统研究。阐明了:

1社会性昆虫的社会行为和社会组织基因组演化机制(Science 2010 共同一作; Science 2015 共同通讯作者);

2蚂蚁行为和形态等级分化的遗传和神经生物学基础(Nature Communications 2014 共同通讯作者);

3蚂蚁等级分化的表观遗传性基础(Current Biology 2012 共同通讯作者);

4)蚂蚁与其他物种的共生及共同演化机制(Genome Research 2011 共同一作; Nature Communications 2016 共同通讯作者)

目前在开展的研究包括:

1)全球蚂蚁基因组联盟计划(The Global Ant Genomics Alliance, GAGA

全球蚂蚁基因组联盟计划(http://antgenomics.dk/)将构建全球蚁科属级别代表物种的基因组图谱,提供最全面的蚂蚁基因组多样性数据。通过对这些基因组数据的比较分析,我们将可以理解蚂蚁演化的全球性趋势,并找到当今蚂蚁物种的多样性及其令人惊叹的适应性背后的遗传基础。根据我们之前完成的国际鸟类基因组演化项目的经验(Zhang et al. 2014),我们预期在系统发育框架下从全球范围内选取约200个有代表性行为生态特征的蚂蚁物种进行基因组分析,将会极大促进蚂蚁(乃至其他物种)生物学的研究,同时为未来数十年学术界回答不同的科学问题提供了大量的基础数据。

2)蚂蚁个体等级分化的分子遗传机理

蚂蚁的等级分化是一个不可逆的过程,雌性在发育的过程中逐渐分化出了形态、生理和行为均不同的等级:蚁后专职负责繁衍后代,工蚁负责生殖外的其他工作。这一生殖分化与社会分工的发育过程类似于后生动物中个体生殖细胞系和体细胞系的分化过程。然而,与动物发育的巨大进展相比,我们对个体发育中等级分化的分子机制的理解是极其有限的。蚁后和工蚁等级分化的起点是什么时候?在具有相同遗传信息的状态下,蚁后和工蚁的分化是如何调控形成的?这些问题都是我们希望能去解答的。

本课题组以法老蚁(Monomorium pharaonis)作为研究模型,该物种工蚁的卵巢完全退化,彻底丧失生殖能力。而且,工蚁和蚁后早在二龄幼虫期开始已经展现出了外部形态上的差异。这些特征使它成为研究蚂蚁个体等级分化的遗传机理的理想模式物种。利用分子遗传学等方法来确定其等级分化的起点,并通过基因功能验证和表观遗传等手段来确定等级分化的调控机制。

3)蚂蚁生殖分化的神经激素调控机制

动物社会组织的出现是生命演化历程中的重大转折性事件。除了蚁后和工蚁展现出来的等级分化外,在个体发育层面,雌性处女生殖蚁gyne完成交配转变为成熟蚁后queen过程中其生理、行为及生殖力均会发生剧烈变化。并且,交配后的queen打破了大多数动物中生殖会降低自身生存力的规律,她在活跃生殖的同时,寿命也得到了显著增长。

为了揭示蚂蚁生殖分化过程中,影响其生理、行为及大脑可塑性的基因调控事件。本课题组通过转录组分析、单细胞测序和原位测序来追踪法老蚁蚁后建立过程中大脑基因表达的动态变化,并通过基因分子功能验证实验来解析相关神经激素的功能,从而了解蚁后建立过程中决定其生理与行为变化的神经激素调控机制,从个体发育角度挖掘超个体组织系统生殖分化的核心基因调控网络。

  承担科研项目

2018.07-2023.06,中国科学院战略性先导科技专项(B类),鸟类不同类群间及与病毒间的协同演化机制研究,XDB31020202300万元,参与; 

2018.08-2021.12海洋环境安全保障重点专项,企鹅物种进化树、进化格局以及对地质环境变迁的响应,2018YFC1406901228万元,参与; 

2020.01-2022.12,国际大科学计划培育专项,现生鸟类多样性演化历史及机制研究,152453KYSB20170002300万元,主持; 

2020.01-2023.12,国家自然科学基金委员会面上项目,单细胞测序技术揭示蚂蚁大脑神经可塑性,3197057358万元,主持。 

  专家类别
研究员
  社会任职

2011 3-biotech杂志 编委

2011 国际万种脊椎动物基因组联盟(G10K) 中方协调人

2012 国际鸟类演化生物学研究联盟 发起人和领导

2012 国际昆虫基因组联盟(i5K) 委员会成员

2013 Human genomics 杂志 编委

2013 Encyclopedia of Life Sciences杂志 编委

2015 国际万种鸟类基因组联盟(B10K) 发起人和领导者

2015 国际基因组标准委员会 委员会成员

2016 GigaSceince 杂志 编委

2017 全球蚂蚁比较基因组研究联盟(GAGA) 发起人和领导者

2018 地球生物基因组计划委员会 发起人和领导者

  获奖及荣誉

国际奖

2011 Sir Frederick McMaster visiting fellow, CSIRO, Australia

2012 Marie Curie International Incoming Fellowship, European Commission

2015  Lundbeck Fellow, Denmark

2017  The Carlsberg Foundation Distinguished Associate Professor Fellowships

2019  Villum Investigator

国内奖

2010  深圳市高层次专业人才(国家级)

2011  中国科学院百篇优秀论文

2011  云南省优秀科技论文奖(特等奖)

2013  李汝琪动物遗传学奖(全国每两年两名获奖者)

2014  蝙蝠文章获评2013年中国最具影响力文章之一

2014  北极熊基因组文章获评“Cell年度中国论文

2016  深圳市孔雀计划海外高层次人才(B)

2019 2017年度深圳市自然科学奖一等奖

  代表论著

通讯作者和第一作者论文(*通讯作者) (1-54)

1.     L. Chen#, Q. Qiu#, Y. Jiang#, K. Wang#, Z. Lin#, Z. Li#, F. Bibi, Y. Yang, J. Wang, W. Nie, W. Su, G. Liu, Q. Li, W. Fu, X. Pan, C. Liu, J. Yang, C. Zhang, Y. Yin, Y. Wang, Y. Zhao, C. Zhang, Z. Wang, Y. Qin, W. Liu, B. Wang, Y. Ren, R. Zhang, Y. Zeng, R. R. da Fonseca, B. Wei, R. Li, W. Wan, R. Zhao, W. Zhu, Y. Wang, S. Duan, Y. Gao, Y. E. Zhang, C. Chen, C. Hvilsom, C. W. Epps, L. G. Chemnick, Y. Dong, S. Mirarab, H. R. Siegismund, O. A. Ryder, M. T. P. Gilbert, H. A. Lewin, G. Zhang*, R. Heller* and W. Wang* (2019). Large-scale ruminant genome sequencing provides insights into their evolution and distinct traits. Science 364(6446).

2.     S. Feng#, Q. Fang, R. Barnett, C. Li, S. Han, M. Kuhlwilm, L. Zhou, H. Pan, Y. Deng, G. Chen, A. Gamauf, F. Woog, R. Prys-Jones, T. Marques-Bonet, M. T. P. Gilbert and G. Zhang* (2019). The Genomic Footprints of the Fall and Recovery of the Crested Ibis. Current Biology 29(2): 340-349 e347.

3.     Y. He#, H. Pan, G. Zhang* and S. He* (2019). Comparative study on pattern recognition receptors in non-teleost ray-finned fishes and their evolutionary significance in primitive vertebrates. Science China Life Sciences 62(4): 566-578.

4.     H. Pan#, T. L. Cole#, X. Bi, M. Fang, C. Zhou, Z. Yang, D. T. Ksepka, T. Hart, J. L. Bouzat, L. S. Argilla, M. F. Bertelsen, P. D. Boersma, C. A. Bost, Y. Cherel, P. Dann, S. R. Fiddaman, P. Howard, K. Labuschagne, T. Mattern, G. Miller, P. Parker, R. A. Phillips, P. Quillfeldt, P. G. Ryan, H. Taylor, D. R. Thompson, M. J. Young, M. R. Ellegaard, M. T. P. Gilbert, M. S. Sinding, G. Pacheco, L. D. Shepherd, A. J. D. Tennyson, S. Grosser, E. Kay, L. J. Nupen, U. Ellenberg, D. M. Houston, A. H. Reeve, K. Johnson, J. F. Masello, T. Stracke, B. McKinlay, P. G. Borboroglu, D. X. Zhang and G. Zhang* (2019). High-coverage genomes to elucidate the evolution of penguins. Gigascience 8(9).

5.     J. Stiller*. and G. Zhang* (2019). Comparative Phylogenomics, a Stepping Stone for Bird Biodiversity Studies. Diversity 11(7).

6.     Lewin HA#*, Robinsone GE, Kressf WJ, Bakerg WJ, Coddingtonf J, Crandallh KA, Durbini R, Edwardsk SV, Forestg F′, Gilbertm MTP, Goldsteino MM, Grigorievp IV, Hackettr KJ, Hausslers D, Jarvisu ED, Johnsonv WE, Patrinosw A, Richardsx S, Castilla-Rubioy JC, van Sluys MA, Soltiscc PS, Xu X, Yang HM, and Zhang GJ*. 2018. Earth BioGenome Project: Sequencing life for the future of life. Proceedings of the National Academy of Sciences of the United States of America. 2018. 115(17): p. 4325-4333.

7.     Kukekova AV#*, Johnson JL, Xiang XY, Feng SH, Liu SP, Rando HM, Kharlamova AV, Herbeck Y, Serdyukova NA, Xiong ZJ, Beklemischeva V, Koepfli KP, Gulevich RG, Vladimirova AV, Hekman JP, Perelman PL, Graphodatsky AS, O'Brien SJ, Wang X, Clark AG, Acland GM, Trut LN, Zhang GJ*. 2018. Red fox genome assembly identifies genomic regions associated with tame and aggressive behaviours. Nature Ecology & Evolution. 2018. 2(9): p. 1479-1491.

8.     Zhang GJ#*. 2018. The first AsiaEvo conference, connecting Asian evolutionary biologists to the world. National Science Review. 2018. 5(5): p. 614-616

9.     Zhang, GJ#*. The bird’s-eye view on chromosome evolution. Genome Biology 19, 201 (2018).

10. Qiu BT#, Larsen RS, Chang NC, Wang J, Boomsma JJ*, Zhang GJ*, 2018. Towards reconstructing the ancestral brain gene-network regulating caste differentiation in ants. Nature Ecology & Evolution. 2018. 2(11): p. 1782-1791.

11. Rogers RL#, Zhou L#, Chu C, Márquez R, Corl A, Linderoth T, Freeborn L, MacManes MD, Xiong Z, Zheng J, Guo C, Xun X, Kronforst MR, Summers K, Wu Y, Yang H, Richards-Zawacki CL, Zhang GJ* and Nielsen R*.  Genomic Takeover by Transposable Elements in the Strawberry Poison Frog. Molecular Biology and Evolution. 2018. 35(12): 2913-2927.

12. Zhang CZ #, Chen L#, Zhou Y#, Wang K, Chemnick LG, Ryder OA, Wang W, Zhang GJ* and Qiu Q*. 2017. Draft genome of the milu (Elaphurus davidianus). Gigascience. 2017. 7(2).

13. Avalos A, Pan H, Li C, Acevedo Gonzalez JP, Rendon G, Fields CJ, Brown PJ, Giray T, Robinson GE*, Hudson ME*, Zhang G*. A soft selective sweep during rapid evolution of gentle behaviour in an Africanized honeybee. Nat Commun, 2017, 8:1550.(Rane, Clarke et al. 2019)

14. Hargreaves A, Zhou L, Christensen J, Marlétaz F, Liu S, Li F, Jansen P, Spiga E, Hansen M, Pedersen S, Biswas S, Serikawa K, Fox B, Taylor W, Mulley J, Zhang G*, Heller R*, Holland P*. Genome sequence of a diabetes-prone rodent reveals a mutation hotspot around the ParaHox gene cluster. Proc Natl Acad Sci U S A, 2017, 114(29):7677-7682.

15. Gao J, Li Q, Wang Z, Zhou Y, Martelli P, Li F, Xiong Z, Wang J, Yang H, Zhang G*. Sequencing, de novo assembling and annotating the genome of the endangered Chinese crocodile lizard Shinisaurus crocodilurus. GigaScience, 2017, 6(7):1-6.

16. Boomsma J, Brady S, Dunn R, Gadau J, Heinze J, Keller L, Moreau C, Sanders N, Schrader L, Schultz T, Sundstrom L, Ward P, Wcislo W, Zhang G* & The GAGA Consortium. Forum The Global Ant Genomics Alliance (GAGA). Myrmecol News, 2017, 25(2):61-66.

17. Seki R, Li C, Fang Q, Hayashi S, Egawa S, Hu J, Xu L, Pan H, Kondo M, Sato T, Matsubara H, Kamiyama N, Kitajima K, Saito D, Liu Y, Gilbert TM, Zhou Q, Xu X, Shiroishi T, Irie N*, Tamura K*. & Zhang G*. Functional roles of Aves class-specific cis-regulatory elements on macroevolution of bird-specific features. Nat Commun, 2017, 8, 14229.

18. Xiong Z, Li F, Li Q, Zhou L, Gamble T, Zheng J, Kui L, Li C, Li S, Yang H, Zhang G*. Draft genome of the leopard gecko, Eublepharis macularius. GigaScience, 2016, 5: 49.

19. Pan H, Yu H, Ravi V, Li C, Lee PA, Lian MM, Tay BH, Brenner S, Wang J, Yang H, Zhang G*, Venkatesh B*. The genome of the largest bony fish, ocean sunfish (Mola mola), provides insights into its fast growth rate. GigaScience, 2016, 5 (1):36.

20. Wang Z, Lian J, Li Q, Zhang P, Zhou Y, Zhan X, Zhang G*. RES-Scanner: a software package for genome-wide identification of RNA-editing sites. GigaScience, 2016, 5 (1): 37.

21. Nygaard S, Hu H, Li, C, Schi?tt M, Chen Z, Yang Z, Xie Q, Ma C, Deng Y, Dikow BR, Rabeling C, Nash RD, Wcislo TW, Brady GS, Schultz RT, Zhang G*, Boomsma J*. Reciprocal genomic evolution in the ant-fungus agricultural symbiosis. Nat Commun, 2016, 7.

22. Zhang G*, Rahbek C, Graves GR, Lei F, Jarvis ED, & Gilbert MT. Genomics: Bird sequencing project takes off. Nature, 2015, 522(7554):34.

23. Jarvis ED, Mirarab S, Aberer AJ, Li B, Houde P, Li C, Ho SY, Faircloth BC, Nabholz B, Howard JT, Suh A, Weber CC, da Fonseca RR, Alfaro-Nunez A, Narula N, Liu L, Burt D, Ellegren H, Edwards SV, Stamatakis A, Mindell DP, Cracraft J, Braun EL, Warnow T, Jun W, Gilbert MT, Zhang G, & Avian Phylogenomics C. Phylogenomic analyses data of the avian phylogenomics project. Gigascience, 2015, 4:4.

24. Zhang J, Li C, Zhou Q, &Zhang G*. Improving the ostrich genome assembly using optical mapping data. Gigascience, 2015, 4:24.

25. Georges A*, Li Q, Lian J, O'Meally D, Deakin J, Wang Z, Zhang P, Fujita M, Patel HR, Holleley CE, Zhou Y, Zhang X, Matsubara K, Waters P, Graves JA, Sarre SD, & Zhang G*. High-coverage sequencing and annotated assembly of the genome of the Australian dragon lizard Pogona vitticeps. Gigascience, 2015, 4:45.

26. Kapheim KM, Pan H, Li C, Salzberg SL, Puiu D, Magoc T, Robertson HM, Hudson ME, Venkat A, Fischman BJ, Hernandez A, Yandell M, Ence D, Holt C, Yocum GD, Kemp WP, Bosch J, Waterhouse RM, Zdobnov EM, Stolle E, Kraus FB, Helbing S, Moritz RF, Glastad KM, Hunt BG, Goodisman MA, Hauser F, Grimmelikhuijzen CJ, Pinheiro DG, Nunes FM, Soares MP, Tanaka ED, Simoes ZL, Hartfelder K, Evans JD, Barribeau SM, Johnson RM, Massey JH, Southey BR, Hasselmann M, Hamacher D, Biewer M, Kent CF, Zayed A, Blatti C, 3rd, Sinha S, Johnston JS, Hanrahan SJ, Kocher SD, Wang J*, Robinson GE*, & Zhang G*. Social evolution. Genomic signatures of evolutionary transitions from solitary to group living. Science, 2015, 348(6239):1139-1143.

27. Zhang G*, Jarvis ED, & Gilbert MT. Avian genomes. A flock of genomes. Introduction. Science, 2014,346(6215):1308-1309.

28. Zhang G*, Li B, Li C, Gilbert MT, Jarvis ED, Wang J, & Avian Genome C. Comparative genomic data of the Avian Phylogenomics Project. Gigascience, 2014, 3(1):26.

29. Chen L, Tang L, Xiang H, Jin L, Li Q, Dong Y, Wang W*, & Zhang G*. Advances in genome editing technology and its promising application in evolutionary and ecological studies. Gigascience, 2014, 3:24.

30. Jarvis ED*, Mirarab S, Aberer AJ, Li B, Houde P, Li C, Ho SY, Faircloth BC, Nabholz B, Howard JT, Suh A, Weber CC, da Fonseca RR, Li J, Zhang F, Li H, Zhou L, Narula N, Liu L, Ganapathy G, Boussau B, Bayzid MS, Zavidovych V, Subramanian S, Gabaldon T, Capella-Gutierrez S, Huerta-Cepas J, Rekepalli B, Munch K, Schierup M, Lindow B, Warren WC, Ray D, Green RE, Bruford MW, Zhan X, Dixon A, Li S, Li N, Huang Y, Derryberry EP, Bertelsen MF, Sheldon FH, Brumfield RT, Mello CV, Lovell PV, Wirthlin M, Schneider MP, Prosdocimi F, Samaniego JA, Vargas Velazquez AM, Alfaro-Nunez A, Campos PF, Petersen B, Sicheritz-Ponten T, Pas A, Bailey T, Scofield P, Bunce M, Lambert DM, Zhou Q, Perelman P, Driskell AC, Shapiro B, Xiong Z, Zeng Y, Liu S, Li Z, Liu B, Wu K, Xiao J, Yinqi X, Zheng Q, Zhang Y, Yang H, Wang J, Smeds L, Rheindt FE, Braun M, Fjeldsa J, Orlando L, Barker FK, Jonsson KA, Johnson W, Koepfli KP, O'Brien S, Haussler D, Ryder OA, Rahbek C, Willerslev E, Graves GR, Glenn TC, McCormack J, Burt D, Ellegren H, Alstrom P, Edwards SV, Stamatakis A, Mindell DP, Cracraft J, Braun EL, Warnow T, Jun W*, Gilbert MT*& Zhang G*. Whole-genome analyses resolve early branches in the tree of life of modern birds. Science, 2014, 346(6215):1320-1331. (Flagship paper in Special Issue of Avian phylogenomics Project)

31. Zhou Q*, Zhang J, Bachtrog D, An N, Huang Q, Jarvis ED, Gilbert MT, & Zhang G*. Complex evolutionary trajectories of sex chromosomes across bird taxa. Science, 2014, 346(6215):1246338.

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84. Zhang G, Fang X, Guo X, Li L, Luo R, Xu F, Yang P, Zhang L, Wang X, Qi H, Xiong Z, Que H, Xie Y, Holland PW, Paps J, Zhu Y, Wu F, Chen Y, Wang J, Peng C, Meng J, Yang L, Liu J, Wen B, Zhang N, Huang Z, Zhu Q, Feng Y, Mount A, Hedgecock D, Xu Z, Liu Y, Domazet-Loso T, Du Y, Sun X, Zhang S, Liu B, Cheng P, Jiang X, Li J, Fan D, Wang W, Fu W, Wang T, Wang B, Zhang J, Peng Z, Li Y, Li N, Wang J, Chen M, He Y, Tan F, Song X, Zheng Q, Huang R, Yang H, Du X, Chen L, Yang M, Gaffney PM, Wang S, Luo L, She Z, Ming Y, Huang W, Zhang S, Huang B, Zhang Y, Qu T, Ni P, Miao G, Wang J, Wang Q, Steinberg CE, Wang H, Li N, Qian L, Zhang G, Li Y, Yang H, Liu X, Wang J, Yin Y, & Wang J. The oyster genome reveals stress adaptation and complexity of shell formation. Nature, 2012, 490(7418):49-54.

85. Young ND, Jex AR, Li B, Liu S, Yang L, Xiong Z, Li Y, Cantacessi C, Hall RS, Xu X, Chen F, Wu X, Zerlotini A, Oliveira G, Hofmann A, Zhang G, Fang X, Kang Y, Campbell BE, Loukas A, Ranganathan S, Rollinson D, Rinaldi G, Brindley PJ, Yang H, Wang J, Wang J, & Gasser RB. Whole-genome sequence of Schistosoma haematobium. Nat Genet, 2012,44(2):221-225.

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87. Jex AR*, Liu S, Li B, Young ND, Hall RS, Li Y, Yang L, Zeng N, Xu X, Xiong Z, Chen F, Wu X, Zhang G, Fang X, Kang Y, Anderson GA, Harris TW, Campbell BE, Vlaminck J, Wang T, Cantacessi C, Schwarz EM, Ranganathan S, Geldhof P, Nejsum P, Sternberg PW, Yang H, Wang J*, Wang J*, & Gasser RB*. Ascaris suum draft genome. Nature, 2011, 479(7374):529-533.

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近五年发表的10篇代表性论文 (*通讯作者)

1.  Qiu BT#, Larsen RS, Chang NC, Wang J, Boomsma JJ*, Zhang GJ*, 2018. Towards reconstructing the ancestral brain gene-network regulating caste differentiation in ants. Nature Ecology & Evolution. 2018. 2(11): p. 1782-1791

2.  Avalos A, Pan H, Li C, Acevedo Gonzalez JP, Rendon G, Fields CJ, Brown PJ, Giray T, Robinson GE*, Hudson ME*, Zhang G*. A soft selective sweep during rapid evolution of gentle behaviour in an Africanized honeybee. Nat Commun, 2017, 8:1550.

3.  Nygaard S, Hu H, Li, C, Schi?tt M, Chen Z, Yang Z, Xie Q, Ma C, Deng Y, Dikow BR, Rabeling C, Nash RD, Wcislo TW, Brady GS, Schultz RT, Zhang G*, Boomsma J*. Reciprocal genomic evolution in the ant-fungus agricultural symbiosis. Nat Commun, 2016, 7.

4.  Kapheim KM, Pan H, Li C, Salzberg SL, Puiu D, Magoc T, Robertson HM, Hudson ME, Venkat A, Fischman BJ, Hernandez A, Yandell M, Ence D, Holt C, Yocum GD, Kemp WP, Bosch J, Waterhouse RM, Zdobnov EM, Stolle E, Kraus FB, Helbing S, Moritz RF, Glastad KM, Hunt BG, Goodisman MA, Hauser F, Grimmelikhuijzen CJ, Pinheiro DG, Nunes FM, Soares MP, Tanaka ED, Simoes ZL, Hartfelder K, Evans JD, Barribeau SM, Johnson RM, Massey JH, Southey BR, Hasselmann M, Hamacher D, Biewer M, Kent CF, Zayed A, Blatti C, 3rd, Sinha S, Johnston JS, Hanrahan SJ, Kocher SD, Wang J*, Robinson GE*, & Zhang G*. Social evolution. Genomic signatures of evolutionary transitions from solitary to group living. Science, 2015, 348(6239):1139-1143.

5.  Zhang G*, Rahbek C, Graves GR, Lei F, Jarvis ED, & Gilbert MT. Genomics: Bird sequencing project takes off. Nature, 2015, 522(7554):34.

6.  Zhang G*, Jarvis ED, & Gilbert MT. Avian genomes. A flock of genomes. Introduction. Science, 2014, 346(6215):1308-1309.

7.  Jarvis ED*, Mirarab S, Aberer AJ, Li B, Houde P, Li C, Ho SY, Faircloth BC, Nabholz B, Howard JT, Suh A, Weber CC, da Fonseca RR, Li J, Zhang F, Li H, Zhou L, Narula N, Liu L, Ganapathy G, Boussau B, Bayzid MS, Zavidovych V, Subramanian S, Gabaldon T, Capella-Gutierrez S, Huerta-Cepas J, Rekepalli B, Munch K, Schierup M, Lindow B, Warren WC, Ray D, Green RE, Bruford MW, Zhan X, Dixon A, Li S, Li N, Huang Y, Derryberry EP, Bertelsen MF, Sheldon FH, Brumfield RT, Mello CV, Lovell PV, Wirthlin M, Schneider MP, Prosdocimi F, Samaniego JA, Vargas Velazquez AM, Alfaro-Nunez A, Campos PF, Petersen B, Sicheritz-Ponten T, Pas A, Bailey T, Scofield P, Bunce M, Lambert DM, Zhou Q, Perelman P, Driskell AC, Shapiro B, Xiong Z, Zeng Y, Liu S, Li Z, Liu B, Wu K, Xiao J, Yinqi X, Zheng Q, Zhang Y, Yang H, Wang J, Smeds L, Rheindt FE, Braun M, Fjeldsa J, Orlando L, Barker FK, Jonsson KA, Johnson W, Koepfli KP, O'Brien S, Haussler D, Ryder OA, Rahbek C, Willerslev E, Graves GR, Glenn TC, McCormack J, Burt D, Ellegren H, Alstrom P, Edwards SV, Stamatakis A, Mindell DP, Cracraft J, Braun EL, Warnow T, Jun W*, Gilbert MT* & Zhang G*. Whole-genome analyses resolve early branches in the tree of life of modern birds. Science, 2014, 346(6215):1320-1331. (Flagship paper in Special Issue of Avian phylogenomics Project)

8.  Zhang G*, Li C, Li Q, Li B, Larkin DM, Lee C, Storz JF, Antunes A, Greenwold MJ, Meredith RW, Odeen A, Cui J, Zhou Q, Xu L, Pan H, Wang Z, Jin L, Zhang P, Hu H, Yang W, Hu J, Xiao J, Yang Z, Liu Y, Xie Q, Yu H, Lian J, Wen P, Zhang F, Li H, Zeng Y, Xiong Z, Liu S, Zhou L, Huang Z, An N, Wang J, Zheng Q, Xiong Y, Wang G, Wang B, Wang J, Fan Y, da Fonseca RR, Alfaro-Nunez A, Schubert M, Orlando L, Mourier T, Howard JT, Ganapathy G, Pfenning A, Whitney O, Rivas MV, Hara E, Smith J, Farre M, Narayan J, Slavov G, Romanov MN, Borges R, Machado JP, Khan I, Springer MS, Gatesy J, Hoffmann FG, Opazo JC, Hastad O, Sawyer RH, Kim H, Kim KW, Kim HJ, Cho S, Li N, Huang Y, Bruford MW, Zhan X, Dixon A, Bertelsen MF, Derryberry E, Warren W, Wilson RK, Li S, Ray DA, Green RE, O'Brien SJ, Griffin D, Johnson WE, Haussler D, Ryder OA, Willerslev E, Graves GR, Alstrom P, Fjeldsa J, Mindell DP, Edwards SV, Braun EL, Rahbek C, Burt DW, Houde P, Zhang Y, Yang H, Wang J, Avian Genome C, Jarvis ED*, Gilbert MT* & Wang J*. Comparative genomics reveals insights into avian genome evolution and adaptation. Science, 2014, 346(6215):1311-1320. (Flagship paper in Special Issue of Avian phylogenomics Project)

9.  Li Q, Wang Z, Lian J, Schiott M, Jin L, Zhang P, Zhang Y, Nygaard S, Peng Z, Zhou Y, Deng Y, Zhang W, Boomsma JJ*, & Zhang G*. Caste-specific RNA editomes in the leaf-cutting ant Acromyrmex echinatior. Nat Commun, 2014, 5:4943.

10.  Poulsen M, Hu H, Li C, Chen Z, Xu L, Otani S, Nygaard S, Nobre T, Klaubauf S, Schindler PM, Hauser F, Pan H, Yang Z, Sonnenberg AS, de Beer ZW, Zhang Y, Wingfield MJ, Grimmelikhuijzen CJ, de Vries RP, Korb J, Aanen DK, Wang J*, Boomsma JJ*, & Zhang G*. Complementary symbiont contributions to plant decomposition in a fungus-farming termite. Proc Natl Acad Sci U S A, 2014, 111(40):14500-14505.

 

  研究团队

研究人员

赵若苹   高级实验师 zhaorp@mail.kiz.ac.cn

刘薇薇   助理研究员 leigh.7@163.com

赵  洁   实验师 zhaojie129scau@163.com

张海林   实验师 zhanghl0327@mail.kiz.ac.cn

博士后

高琼华    2016 gaoqionghua123@163.com

研究生

李  冀   2018级硕士 liji@mail.kiz.ac.cn

张霞芳   2019级博士 zhangxiafang128@163.com

客座人员

冉  浩   专家顾问 ranhao.cn@gmail.com

冯少鸿   助理研究员 fengshaohong@genomics.cn

熊子 军   研究实习员 xiongzijun@genomics.cn

丁  果   博士研究生 dzdingo@gmail.com

宁冬冬   硕士研究生 274399033@qq.com

陈  俊   本科生 1323389400@qq.com

李儒岩   本科生 shlry888@sjtu.edu.cn

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