专家人才     首页 > 研究队伍
姚永刚  研究员
疾病机理遗传学与进化医学学科组
职  务: 所长
学  历:
电  话: +86 871 68125440
传  真: +86 871 68125440
电子邮件: yaoyg@mail.kiz.ac.cn
通讯地址: 云南省昆明市盘龙区龙欣路17号 中国科学院昆明动物研究所 动物模型与人类疾病机理重点实验室    650201
其他主页: http://mitotool.kiz.ac.cn/lab/index.html
  简  历

姚永刚博士,研究员,博士生导师。1997年毕业于安徽师范大学生物系获学士学位,2003年于中国科学院昆明动物研究所/中科院研究生院获博士学位。20032-20049月在约翰霍普金斯大学医学院(Johns Hopkins University School of Medicine)从事博士后研究工作,200410-20081月在美国国家健康研究院心脏、肺、血液研究所(National Heart, Lung, and Blood Institute, NIH)从事博士后研究工作。200712月回昆明动物研究所工作,现为疾病机理遗传学与进化医学学科组负责人。已在Am J Hum GenetAutophagyPNASAlzheimers DementRedox BiolSCI期刊发表论文和评述270余篇,被SCI引用8530多次,h指数=49(截止2022531日)。先后获得朱李月华优秀教师奖、国家自然科学奖二等奖(第二获奖人)、新世纪百千万人才工程国家级人选、云南省有突出贡献优秀专业技术人才奖等奖项与荣誉称号。2009年获得国家杰出青年基金和云南省高端科技人才计划资助,先后承担中科院战略性科技专项(B类)和前沿重点部署项目、国家基金委重点和面上项目等。现担任“Zoological Research Associate Editor (2010.12 - 2012.08) 和主编(Editor-in-chief, 2012.09- )、“Journal of Genetics and Genomics (2010- )和“Cellular and Molecular Neurobiology(2018-) Editorial Board Member、“Journal of Human Genetics Associate Editor (2011- )、“Infection, Genetics and Evolution Receiving Editor (2012- )、“PLoS ONE Academic Editor (2012- )、“Scientific Reports Editorial Board Member (2016- )

  研究方向

致力于人类疾病遗传机制与进化医学研究,按照EAFE = Evolutionary analysis; A = Association study; F = Functional assay)三层次,带领团队深入开展神经和免疫系统相关疾病的遗传基础与分子机制解析,通过对阿尔茨海默症等神经系统疾病和感染性疾病麻风的集中研究,试图阐明机体神经系统与免疫系统紊乱和病变导致的复杂临床表型的遗传基础与机理。力争将复杂纷繁的科研工作变得“Easier And Fun”。同时,集中开展实验动物树鼩生物学、遗传修饰和品系创制研究。

实验室主页:http://mitotool.kiz.ac.cn/lab/index.html

  承担科研项目

1)阿尔茨海默症等疾病遗传易感基础与分子机制

2)线粒体、自噬与疾病

3)树鼩生物学与遗传修饰

  专家类别
研究员;杰青;百千万人才
  社会任职
  获奖及荣誉

2014    云南省科学技术奖励二等奖(自然科学奖); 项目名称: Leber遗传性视神经病遗传易感分析; 获奖人员: 姚永刚、张阿梅、余丹丹、毕蕊. 

2012    中国科学院 朱李月华优秀教师奖 

2010    云南省有突出贡献优秀专业技术人才奖 二等奖 (一等奖空缺) 

2009    新世纪百千万人才工程国家级人选 

2006    国家自然科学奖二等奖; 项目名称: 线粒体基因组多样性与东亚人群历史的研究; 获奖人员: 张亚平、姚永刚、孔庆鹏、丁远春、孙昌. 

2005    全国百篇优秀博士论文 

2002    中国科学院院长奖特别奖. 

  代表论著

1.   Zeng J*, Xie X, Feng X-L, Xu L, Han J-B, Yu D, Zou Q-C, Liu Q, Li X, Ma G, Li M-H*, Yao Y-G*. 2022. Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice.  EBioMedicine, 75: 103803 (doi: 10.1016/j.ebiom.2021.103803)

2.   Qin D-D, Zhou J-K, He X-C, Shen X-Y, Li C, Chen H-Z, Yan L-Z, Hu Z-F, Li X, Lv L-B, Yao Y-G*, Wang Z*, Huang X-X*, Hu X-T*, Zheng P*. 2021. Depletion of giant ANK2 in monkeys causes drastic brain volume loss. Cell Discovery, 7: 113 (doi: 10.1038/s41421-021-00336-4)

3.   Gu T, Yu D, Xu L, Yao Y-L, Yao Y-G*. 2021. Tupaia GBP1 interacts with STING to initiate autophagy and restrict herpes simplex virus type 1 infection. Journal of Immunology, 207: 2673-2680

4.   Liu Q, Gu T, Su L-Y, Jiao L, Qiao X, Xu M, Xie T, Yang LX, Yu D, Xu L, Chen C*, Yao Y-G*. 2021. GSNOR facilitates antiviral innate immunity by restricting TBK1 cysteine S-nitrosation. Redox Biology, 47: 102172 (doi: 10.1016/j.redox.2021.102172)

5.   Ye M-S, Zhang J-Y, Yu D-D, Xu M, Xu L, Lv L-B, Zhu Q-Y, Fan Y, Yao Y-G*. 2021. Comprehensive annotation of the Chinese tree shrew genome by large-scale RNA sequencing and long-read isoform sequencing. Zoological Research, 42: 692-709.

6.   Luo R*, Fan Y, Yang J, Ye M, Zhang D-F, Guo K, Li X, Bi R, Xu M, Yang LX, Li Y, Ran X, Jiang H-Y, Zhang C, Tan L, Sheng N, Yao Y-G*. 2021. A novel missense variant in ACAA1 contributes to early-onset Alzheimer's disease, impairs lysosomal function, and facilitates amyloid-β pathology and cognitive decline. Signal Transduction and Targeted Therapy, 6: 325 (doi: 10.1038/s41392-021-00748-4)

7.   Li H, Su L-Y, Yang L, Li M, Liu Q, Li Z, Hu Y, Li H, Wu S, Wang W, Hu Y, Wang Z, Rizak JD, Huang B, Xu M, Wu J, Lv L-B, Turck CW*, Yin Y*, Yao Y-G*, Su B*, Hu X*. 2021. A cynomolgus monkey with naturally occurring Parkinson's disease. National Science Review, 8: nwaa292 (doi: 10.1093/nsr/nwaa292)

8.   Tang X-H, Luo R-C, Ye M-S, Tang H-Y, Ma Y-L, Chen Y-N, Wang X-M, Lu Q-Y, Liu S, Li X-N, Yan Y, Yang J, Ran X-Q, Fang X, Zhou Y, Yao Y-G*, Di Y-T*, Hao X-J*. 2021. Harpertrioate A, an A,B,D-seco-Limonoid with promising biological activity against Alzheimer's disease from twigs of Harrisonia perforata (Blanco) Merr. Organic Letters, 23: 262-267

9.   Zheng H-Y, Xu M, Yang C-X, Tian R-R, Zhang M, Li JJ, Wang X-C, Ding Z-L, Li G-M, Li X-L, He Y-Q, Dong X-Q*, Yao Y-G*, Zheng Y-T*. 2020. Longitudinal transcriptome analyses show robust T cell immunity during recovery from COVID-19. Signal Transduction and Targeted Therapy, 5(1): 294 (doi: 10.1038/s41392-020-00457-4)

10. Yao Y-L, Yu D, Xu L, Gu T, Li Y, Zheng X, Bi R, Yao Y-G*. 2020. Tupaia OASL1 promotes cellular antiviral immune responses by recruiting MDA5 to MAVS. Journal of Immunology, 205: 3419-3428.

11. Xu L, Yu D-D, Ma Y-H, Yao Y-L, Luo R-H, Feng X-L, Cai H-R, Han J-B, Wang X-H, Li M-H, Ke C-W, Zheng Y-T*, Yao Y-G*. 2020. COVID-19-like symptoms observed in Chinese tree shrews infected with SARS-CoV-2. Zoological Research, 41: 517-526.

12. Xu L, Yu D, Yao YL, Gu T, Zheng X, Wu Y, Luo R-H, Zheng Y-T, Zhong J, Yao Y-G*. 2020. Tupaia MAVS is a dual target during hepatitis C virus infection for innate immune evasion and viral replication via NF-κB. Journal of Immunology, 205: 2091-2099 (doi: 10.4049/jimmunol.2000376)

13. Wu Y, Li X, Liu J, Luo X-J*, Yao Y-G*. 2020. SZDB2.0: an updated comprehensive resource for schizophrenia research. Human Genetics, 139: 1285-1297 (doi: 10.1007/s00439-020-02171-1)

14. Xu L, Yu D, Peng L, Wu Y, Fan Y, Gu T, Yao Y-L, Zhong J, Chen X, Yao Y-G*. 2020. An alternative splicing of Tupaia STING modulated anti-RNA virus responses by targeting MDA5-LGP2 and IRF3. The Journal of Immunology, 204: 3191-3204.

15. Liu Q, Su L-Y*, Sun C, Jiao L, Miao Y, Xu M, Luo R, Zuo X, Zhou R, Zheng P, Xiong W, Xue T, Yao Y-G*. 2020. Melatonin alleviates morphine analgesic tolerance in mice by decreasing NLRP3 inflammasome activation. Redox Biology, 34: 101560.

16. Luo R, Su L-Y, Li G, Yang J, Liu Q, Yang L-X, Zhang D-F, Zhou H, Xu M, Fan Y, Li J, Yao Y-G*. 2020. Activation of PPARA-mediated autophagy reduces Alzheimer’s disease-like pathology and cognitive decline in a murine model. Autophagy, 16: 52-69 (doi: 10.1080/15548627.2019.1596488)

17. Fan Y, Ye M-S, Zhang J-Y, Xu L, Yu D-D, Gu T-L, Yao Y-L, Chen J-Q, Lv L-B, Zheng P, Wu D-D, Zhang G-J, Yao Y-G*. 2019. Chromosomal level assembly and population sequencing of the Chinese tree shrew genome. Zoological Research, 40: 506-521 (doi: 10.24272/j.issn.2095-8137.2019.063)

18. Wu Y, Bi R, Zeng C, Ma C, Sun C, Li J, Xiao X, Li M, Zhang D-F, Zheng P, Sheng N*, Luo X-J*, Yao Y-G*. 2019. Identification of the primate-specific gene BTN3A2 as an additional schizophrenia risk gene in the MHC loci. EBioMedicine, 44: 530-541 (doi: 10.1016/j.ebiom.2019.05.006)

19. Zhang D-F, Fan Y, Xu M, Wang G, Wang D, Li J, Kong L-L, Zhou H, Luo R, Bi R, Wu Y, Li G-D, Alzheimer's Disease Neuroimaging Initiative, Li M, Luo X-J, Jiang H-Y, Tan L, Zhong C, Fang Y, Zhang C, Sheng N, Jiang T, Yao Y-G*. 2019. Complement C7 is a novel risk gene for Alzheimer's disease in Han Chinese. National Science Review, 6: 257-274 (doi: https://doi.org/10.1093/nsr/nwy127)

20. Xu L, Peng L, Gu T, Yu D, Yao Y-G*. 2019. The 3'UTR of human MAVS mRNA contains multiple regulatory elements for the control of protein expression and subcellular localization. Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 1862: 47-57

21. Bi R*, Zhang W, Zhang D-F, Xu M, Fan Y, Hu Q-X, Jiang H-Y, Tan L, Li T, Fang Y, Zhang C, Yao Y-G*. 2018. Genetic association of the cytochrome c oxidase-related genes with Alzheimer’s disease in Han Chinese. Neuropsychopharmacology, 43: 2264-2276 (doi:10.1038/s41386-018-0144-3)

22. Wang D, Fan Y, Malhi M, Bi R, Wu Y, Xu M, Yu X-F, Long H, Li Y-Y, Zhang D-F*, Yao Y-G*. 2018. Missense variants in HIF1A and LACC1 contribute to leprosy risk in Han Chinese. American Journal of Human Genetics, 102: 794-805.

23. Fan Y, Luo R, Su L-Y, Xiang Q, Yu D, Xu L, Chen J-Q, Bi R, Wu D-D, Zheng P*, Yao Y-G*. 2018. Does the genetic feature of the Chinese tree shrew (Tupaia belangeri chinensis) support its potential as a viable model for Alzheimer’s disease research? Journal of Alzheimer’s Disease, 61: 1015-1028 (doi: 10.3233/JAD-170594)

24. Wang D*, Zhang D-F, Li GD, Bi R, Fan Y, Wu Y, Yu X-F, Long H, Li Y-Y, Yao Y-G*. 2018. A pleiotropic effect of the APOE gene: association of APOE polymorphisms with multibacillary leprosy in Han Chinese from Southwest China. British Journal of Dermatology, 178: 931-939.

25. Xu M, Zhang D-F*, Luo R, Wu Y, Zhou H, Kong L-L, Bi R, Yao Y-G*. 2018. A systematic integrated analysis of brain expression profiles reveals YAP1 and other prioritized hub genes as important upstream regulators in Alzheimer's disease. Alzheimer’s & Dementia, 14: 215-229 (doi: 10.1016/j.jalz.2017.08.012)

26. Su L-Y, Luo R, Liu Q, Su J-R, Yang L-X, Ding Y-Q, Xu L*, Yao Y-G*. 2017. Atg5- and Atg7-dependent autophagy in dopaminergic neurons regulates cellular and behavioral responses to morphine. Autophagy, 13: 1496-1511

27. Tang J, Fan Y, Li H, Xiang Q, Zhang D-F, Li Z, He Y, Liao Y, Wang Y, He F, Zhang F, Shugart YY, Liu C, Tang Y*, Chan RCK*, Wang C-Y*, Yao Y-G*, Chen X*. 2017. Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia. Journal of Genetics and Genomics, 44: 295-306

28. Yao Y-G*. 2017. Creating animal models, why not use the Chinese tree shrew (Tupaia belangeri chinensis)? Zoological Research, 38: 118-126

29. Li G-D, Bi R, Zhang D-F, Xu M, Luo R, Wang D; Alzheimer's Disease Neuroimaging Initiative (ADNI)., Fang Y, Li T, Zhang C, Yao Y-G*. 2017. Female-specific effect of the BDNF gene on Alzheimer's disease. Neurobiology of Aging, 53: 192.e11 - 192.e19 (doi: 10.1016/j.neurobiolaging.2016.12.023)

30. Li C-H, Yan L-Z, Ban W-Z, Tu Q, Wu Y, Wang L, Bi R, Ji S, Ma Y-H, Nie W-H, Lv L-B, Yao Y-G*, Zhao X-D*, Zheng P*. 2017. Long-term propagation of tree shrew spermatogonial stem cells in culture and successful generation of transgenic offspring. Cell Research, 27: 241-252

31. Wu Y, Yao Y-G*, Luo X-J*. 2017. SZDB: a database for schizophrenia genetic research. Schizophrenia Bulletin, 43: 459-471

32. Xu L, Yu D, Fan Y, Peng L, Wu Y, Yao Y-G*. 2016. Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew. Proceedings of the National Academy of Sciences of the United States of America, 113: 10950-10955

33. Zhang C, Zhang D-F, Wu Z-G, Peng D-H, Chen J, Ni J, Tang W, Xu L, Yao Y-G*, Fang Y-R*. 2016. Complement factor H and susceptibility to major depressive disorder in Han Chinese. British Journal of Psychiatry, 208: 446-452

34. Bi R, Tang J, Zhang W, Li X, Chen S-Y, Yu D, Chen X, Yao Y-G*. 2016. Mitochondrial genome variations and functional characterization in Han Chinese families with schizophrenia. Schizophrenia Research, 171: 200-206

35. Zhang D-F*, Wang D, Li Y-Y, Yao Y-G*. 2016. Integrative analyses of leprosy susceptibility genes indicate a common autoimmune profile. Journal of Dermatological Science, 82: 18-27 (doi: 10.1016/j.jdermsci.2016.01.001)

36. Zhang D-F, Li J, Wu H, Cui Y, Bi R, Zhou H-J, Wang H-Z, Zhang C, Wang D; Alzheimer's Disease Neuroimaging Initiative (ADNI), Kong Q-P, Li T, Fang Y, Jiang T*, Yao Y-G*. 2016. CFH variants affect structural and functional brain changes and genetic risk of Alzheimer's disease. Neuropsychopharmacology, 41: 1034-1045

37. Su L-Y, Li H, Lv L, Feng Y-M, Li G-D, Luo R, Zhou H-J, Lei X-G, Ma L, Li J-L, Xu L, Hu X-T*, Yao Y-G*. 2015. Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation. Autophagy, 11: 1745-1759

38. Bi R, Zhang W, Yu D, Li X, Wang H-Z, Hu Q-X, Zhang C, Lu W, Ni J, Fang Y, Li T, Yao Y-G*. 2015. Mitochondrial DNA haplogroup B5 confers genetic susceptibility to Alzheimer's disease in Han Chinese. Neurobiology of Aging, 36: 1604.e7-1604.e16 (doi: org/10.1016/j.neurobiolaging.2014.10.009)

39. Wang D, Xu L, Lv L, Su L-Y, Zhang D-F, Bi R, Yu D, Zhang W, Fan Y, Li X-A, Li Y-Y, Yao Y-G*. 2015. Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China. Genes and Immunity, 16: 112-119

40. Zhang W, Xiao MS, Ji S, Tang J, Xu L, Li X, Li M, Wang HZ, Jiang HY, Zhang DF, Wang J, Zhang S, Xu XF, Yu L, Zheng P, Chen X, Yao Y-G*. 2014. Promoter variant rs2301228 on the neural cell adhesion molecule 1 gene conferring risk of schizophrenia in Han Chinese. Schizophrenia Research, 160: 88-96 (doi: 10.1016/j.schres.2014.09.036)

41. Zhang W, Tang J, Zhang A-M, Peng M-S, Xie H-B, Tan L, Xu L, Zhang Y-P, Chen X*, Yao Y-G*. 2014. A matrilineal genetic legacy from the last glacial maximum confers susceptibility to schizophrenia in Han Chinese. Journal of Genetics and Genomics, 41: 397-407 (http://dx.doi.org/10.1016/j.jgg.2014.05.004)

42. Feng Y-M, Jia Y-F, Su L-Y, Wang D, Lv L, Xu L*, Yao Y-G*. 2013. Decreased mitochondrial DNA copy number in the hippocampus and peripheral blood during opiate addiction is mediated by autophagy and can be salvaged by melatonin. Autophagy, 9: 1395-1406

43. Fan L, Yao Y-G*. 2013. An update to MitoTool: Using a new scoring system for faster mtDNA haplogroup determination. Mitochondrion, 13: 360-363

44. Zhang D-F, Huang X-Q, Wang D, Li Y-Y, Yao Y-G*. 2013. Genetic variants of complement genes Ficolin-2, Mannose-binding lectin and Complement factor H are associated with leprosy in Han Chinese from Southwest China. Human Genetics, 132: 629-640

45. Fan Y, Huang Z-Y, Cao C-C, Chen C-S, Chen Y-X, Fan D-D, He J, Hou H-L, Hu L, Hu X-T, Jiang X-T, Lai R, Lang Y-S, Liang B, Liao S-G, Mu D, Ma Y-Y, Niu Y-Y, Sun X-Q, Xia J-Q, Xiao J, Xiong Z-Q, Xu L, Yang L, Zhang Y, Zhao W, Zhao X-D, Zheng Y-T, Zhou J-M, Zhu Y-B, Zhang G-J*, Wang J*, Yao Y-G*. 2013. Genome of the Chinese tree shrew. Nature Communications, 4:1426 (doi: 10.1038/ncomms2416)

46. Yao Y-G*, Kajigaya S, Feng X, Samsel L, McCoy JP, Jr, Torelli G, Young NS. 2013. Accumulation of mtDNA variations in human single CD34+ cells from maternally related individuals: effects of aging and family genetic background. Stem Cell Research, 10:361-370 (http://dx.doi.org/10.1016/j.scr.2013.01.006)

47. Guo H, Zhuang X-Y, Zhang A-M, Zhang W, Yuan Y, Guo L, Yu D-D, Liu J, Yang D-K, Yao Y-G*. 2012. Presence of mutation m.14484T>C in a Chinese family with maternally inherited essential hypertension but no expression of LHON. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1822:1535-1543 (doi: 10.1016/j.bbadis.2012.06.010)

48. Zhang A-M, Jia X, Guo X, Zhang Q*, Yao Y-G*. 2012. Mitochondrial DNA mutation m.10680G>A is associated with Leber hereditary optic neuropathy in Chinese patients. Journal of Translational Medicine,10(1):43 (doi:10.1186/1479-5876-10-43)

49. Fan L, Yao Y-G*. 2011. MitoTool: A web server for the analysis and retrieval of human mitochondrial DNA sequence variations. Mitochondrion, 11: 351-356

50. Zou Y, Zeng Y, Zhang D-F, Zou S-H, Cheng Y-F*, Yao Y-G*. 2010. IDH1 and IDH2 mutations are frequent in Chinese patients with acute myeloid leukemia but rare in other types of hematological disorders. Biochemical and Biophysical Research Communications, 402: 378-383

51. Bi R, Zhang A-M, Zhang W, Kong Q-P, Wu B-L, Yang X-H, Wang D, Zou Y, Zhang Y-P, Yao Y-G*. 2010. The acquisition of an inheritable 50-bp deletion in the human mtDNA control region does not affect the mtDNA copy number in peripheral blood cells. Human Mutation, 31: 538-543

52. Yao Y-G, Salas A, Logan I, Bandelt H-J. 2009. mtDNA data-mining in GenBank needs surveying. American Journal of Human Genetics, 85: 929-933

53. Bandelt H-J, Salas A, Taylor RW, Yao Y-G*. 2009. The exaggerated status of "novel" and "pathogenic" mtDNA sequence variants due to inadequate database searches. Human Mutation, 30: 191-196

54. Ji Y, Zhang A-M, Jia X, Zhang Y-P, Xiao X, Li S, Guo X, Bandelt H-J, Zhang Q, Yao Y-G*. 2008. Mitochondrial DNA haplogroups M7b1'2 and M8a affect clinical expression of Leber Hereditary Optic Neuropathy in Chinese families with the m.11778G→A mutation. American Journal of Human Genetics, 83: 760-768

55. Yao Y-G*, Kong Q-P, Salas A, Bandelt H-J. 2008. Pseudo-mitochondrial genome haunts disease studies. Journal of Medical Genetics, 45: 769-772

56. Yao Y-G*, Childs RW, Kajigaya S, McCoy JP, Jr, Young NS. 2007. Mitochondrial DNA sequence heterogeneity of single CD34+ cells after nonmyeloablative allogeneic stem cell transplantation. Stem Cells, 25:2670-2676

57. Yao Y-G*, Ogasawara Y, Kajigaya S, Molldrem JJ, Falcao RP, Pintao MC, McCoy JC, Jr, Rizzatti EG, Young NS*. 2007. Mitochondrial DNA sequence variation in single cells from leukemia patients. Blood, 109: 756-762

58. Yao Y-G*, Ellison FM, McCoy JP, Jr, Chen J, Young NS. 2007. Age-dependent accumulation of mtDNA mutations in murine hematopoietic stem cells is modulated by the nuclear genetic background. Human Molecular Genetics, 16: 286-294

59. Yao Y-G*, Salas A, Bravi CM, Bandelt H-J. 2006. A reappraisal of complete mtDNA variation in East Asian families with hearing impairment. Human Genetics, 119: 505-515

60. Yao Y-G, Yang HS, Cao Z, Danielsson J, Duh EJ. 2005. Upregulation of placental growth factor by vascular endothelial growth factor via a post-transcriptional mechanism. FEBS Letters, 579: 1227-1234

61. Yao Y-G#, Kong Q-P#, Wang C-Y, Zhu C-L, Zhang Y-P. 2004. Different matrilineal contributions to genetic structure of ethnic populations in Silk-Road region in China. Molecular Biology and Evolution, 21: 2265-2280

62. Yao Y-G, Duh EJ. 2004. VEGF selectively induces Down syndrome critical region 1 gene expression in endothelial cells: a mechanism for feedback regulation of angiogenesis? Biochemical and Biophysical Research Communications, 321: 648-656

63. Yao Y-G*, Macaulay V, Kivisild T, Zhang Y-P, Bandelt H-J. 2003. To trust or not to trust an idiosyncratic mitochondrial data set. American Journal of Human Genetics, 72: 1341-1346

64. Yao Y-G, Kong Q-P, Man X-Y, Bandelt H-J, Zhang Y-P. 2003. Reconstructing the evolutionary history of China: a caveat about inferences drawn from ancient DNA. Molecular Biology and Evolution, 20: 214-219

65. Yao Y-G, Kong Q-P, Bandelt H-J, Kivisild T, Zhang Y-P. 2002. Phylogeographic differentiation of mitochondrial DNA in Han Chinese. American Journal of Human Genetics, 70: 635-651

66. Yao Y-G, Nie L, Harpending H, Fu Y-X, Yuan Z-G, Zhang Y-P. 2002. Genetic relationship of Chinese ethnic populations revealed by mtDNA sequence diversity. American Journal of Physical Anthropology, 118: 63-76

 

  研究团队

工作人员

张登峰 博士 研究员,zhangdengfeng@mail.kiz.ac.cn

余丹丹 硕士 副研究员,yudandan@mail.kiz.ac.cn

毕 蕊 博士 副研究员,birui@mail.kiz.ac.cn

许 凌 博士 副研究员,xuling0502@mail.kiz.ac.cn

   敏    博士   副研究员,xumin@mail.kiz.ac.cn

罗荣灿   博士   副研究员,luorongcan@mail.kiz.ac.cn

刘前进 博士 副研究员,liuqianjin@mail.kiz.ac.cn

李鸿丽   博士   助理研究员,lihongli@mail.kiz.ac.cn

杨禄秀   本科 助理实验师,yangluxiu@mail.kiz.ac.cn

研究生

焦利进 闫忠江 冉晓倩 余丹丹

朱晓嘉 向柏林 郭亚蓉 康伟博 马志宇 李杰希

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