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论文题目: Pepluanols C-D, Two Diterpenoids with Two Skeletons from Euphorbia peplus
作者: Wan LS, Nian Y, Peng XR, Shao LD, Li XN, Yang J, Zhou M, Qiu MH
联系作者: mingzhou@mail.kiz.ac.cn
发表年度: 2018
DOI: doi: 10.1021/acs.orglett.8b01114
摘要:

Pepluanols C and D (1 and 2), featuring unprecedented 5/5/10 with out,out-[7.2.1]bicylcododecane core and 6/6/7/3 fused-ring skeletons, respectively, were isolated from Euphorbia peplus. Their chemical structures and absolute configurations were determined by a series of extensive spectroscopic methods, and X-ray diffraction analysis. In addition, pepluanols C and D showed 31.6 ± 8.3% and 30.5 ± 2.8% peak current inhibition on the Kv1.3 potassium channel at 30 μM

刊物名称: Organic Letters
论文出处: https://pubs.acs.org/doi/10.1021/acs.orglett.8b01114
影响因子: 6.492(2017年)