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论文题目: |
Out of Southern East Asia of the Brown Rat Revealed by Large Scale Genome Sequencing |
作者: |
Zeng L, Ming C, Li Y, Su LY, Su YH, O Otecko N, Dalecky A, Donnellan S, Aplin K, Liu XH, Song Y, Zhibin Z, Esmailizadeh A, Sohrabi SS, Nanaei HA, Liu HQ, Wang MS, Atteynine SA, Rocamora G, Brescia F, Morand S, Irwin DM, Peng MS, Yao YG, Li H, Wu DD, Zhang YP |
联系作者: |
zhangyp@mail.kiz.ac.cn |
发表年度: |
2017 |
DOI: |
doi:10.1093/molbev/msx276 |
摘要: |
The geographic origin and migration of the brown rat (Rattus norvegicus) remain subjects of considerable debate. In this study, we sequenced whole genomes of 110 wild brown rats with a diverse world-wide representation. We reveal that brown rats migrated out of southern East Asia, rather than northern Asia as formerly suggested, into the Middle East and then to Europe and Africa, thousands of years ago. Comparison of genomes from different geographical populations reveals that many genes involved in the immune system experienced positive selection in the wild brown rat |
刊物名称: |
Molecular Biology and Evolution |
论文出处: |
https://academic.oup.com/mbe/article-lookup/doi/10.1093/molbev/msx276 |
影响因子: |
6.202(2016年) |
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