| 论文题目: |
A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta) |
| 作者: |
Wu Jing; Wang Wenchao; Li Lin; Liu Li; Wang Guimei; Tan Heng; Jiang Huihui; Wang Jianhong*; Ma Yuanye*; Hu Xintian* |
| 联系作者: |
yuanma0716@vip.sina.com; xthu@mail.kiz.ac.cn |
| 发表年度: |
2010 |
| DOI: |
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| 摘要: |
The accurate implantation of microelectrodes is a significant difficulty facing many neurophysiologists This paper reports on a new method used to promote the precise positioning of electrode implantation through magnetic resonance imaging (MRI) allowing both the relevant brain structure and the MRI-visible external markers anchored on the skull (In this case rigid glass tubes with a 0 5 mm Internal diameter) to be displayed By referencing these markers the coordinates of the brain target were calculated Using this novel approach recording electrodes were successfully Implanted Into the superior colliculus (SC) of rhesus monkeys with an error <1 mm and its neuronal discharge signals were obtained This new method allows neurophysiologists to precisely target the small deep brain structures of monkeys and study their electrophysiological characteristics in detail. |
| 刊物名称: |
Journal of Neuroscience Methods |
| 论文出处: |
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| 影响因子: |
2.053 (2015) |
