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论文 |
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论文题目: |
Anti-HIV terpenoids from Daphne aurantiaca Diels. stems |
作者: |
Sheng-Zhuo Huang; Xuan Zhang; Qing-Yun Ma; Yong-Tang Zheng; Hao-Fu Dai; Qi Wang; Jun Zhou*; You-Xing Zhao* |
联系作者: |
junzhou3264@126.com; zhaoyouxing@itbb.org.cn |
发表年度: |
2015 |
DOI: |
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摘要: |
Thirteen new sesquiterpenoids, including six guaiane type auranticanols A-F (1, 2, and 4-7) and seven carotene type auranticanols G-M (18-24) were isolated from the stems of Daphne aurantiaca Diels., along with fourteen known sesquiterpenoids (3, 8-17, 25-27) and two known tigliane diterpenoids (28, 29), and their structures were elucidated by extensively analyzing their MS and NMR spectroscopic data. A bioassay of anti-HIV activity indicated that compounds 11, 14, 19, and 28 showed definite activities with EC50 values of 2.138, 0.286, 1.773 and 0.000282 mu g mL(-1) and SI > 93.545, 93.787, 10.243, and 65 177.305, respectively. |
刊物名称: |
Rsc Advances |
论文出处: |
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影响因子: |
3.289 (2015) |
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