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论文题目: Genomic signatures of near-extinction and rebirth of the crested ibis and other endangered bird species
作者: Shengbin Li; Bo Li; Cheng Cheng; Zijun Xiong; Qingbo Liu; Jianghua Lai; Hannah V Carey; Qiong Zhang; Haibo Zheng; Shuguang Wei; Hongbo Zhang; Liao Chang; Shiping Liu; Shanxin Zhang; Bing Yu; Xiaofan Zeng; Yong Hou; Wenhui Nie; Youmin Guo; Teng Chen; Jiuqiang Han; Jian Wang; Jun Wang; Chen Chen 11 , Jiankang Liu 1,4 , Peter J Stambrook; Ming Xu; Guojie Zhang; M Thomas P Gilbert; Huanming Yang*; Erich D Jarvis*; Jun Yu*; Jianqun Yan
联系作者: yanghm@genomics.cn; jarvis@neuro.duke.edu; junyu@big.
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发表年度: 2014
卷: 15
期: 12
页码: e557
摘要: Background 

Nearly a quarter of all avian species is either threatened or nearly threatened. Of these, 73 species are currently being rescued from going extinct in wildlife sanctuaries. One of the previously most critically-endangered is the crested ibis, Nipponia nippon. Once widespread across North-East Asia, by 1981 only seven individuals from two breeding pairs remained in the wild. The recovering crested ibis populations thus provide an excellent example for conservation genomics since every individual bird has been recruited for genomic and demographic studies. 

Results 

Using high-quality genome sequences of multiple crested ibis individuals, its thriving cohabitant, the little egret, Egretta garzetta, and the recently sequenced genomes of 41 other avian species that are under various degrees of survival threats, including the bald eagle, we carry out comparative analyses for genomic signatures of near extinction events in association with environmental and behavioral attributes of species. We confirm that both loss of genetic diversity and enrichment of deleterious mutations of protein-coding genes contribute to the major genetic defects of the endangered species. We further identify that genetic inbreeding and loss-of-function genes in the crested ibis may all constitute genetic susceptibility to other factors including long-term climate change, over-hunting, and agrochemical overuse. We also establish a genome-wide DNA identification platform for molecular breeding and conservation practices, to facilitate sustainable recovery of endangered species. 

Conclusions 

These findings demonstrate common genomic signatures of population decline across avian species and pave a way for further effort in saving endangered species and enhancing conservation genomic efforts.
刊物名称: Genome Biology
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影响因子: 11.313 (2015)
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