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Principal Investigator
Ming Li     
Phone +86 871 65190162;8603
Fax +86 871 65190162
Address #32 Jiaochangdong Road, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
Zip Code 650223
   Education and Appointments:
  Professional Services
   Research Interests:
  Supported Projects:

1、中科院昆明动物研究所“百人计划”启动项目 (280万元) 


  Public Services:
  Selected Publications:

1.         Chang H,# Xiao X,# Li M.* The Schizophrenia Risk Gene ZNF804A: Clinical Associations, Biological Mechanisms and Neuronal Functions. Molecular Psychiatry 2017; 22:944-953.

2.         Chang H,# Hoshina N,# Zhang C,# Ma Y, Cao H, Wang Y, Wu DD, Bergen SE, Landén M, Hultman CM, Preisig M, Kutalik Z, Castelao E, Grigoroiu-Serbanescu M, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Schofield PR, Cichon S, Nöthen MM, The Swedish Bipolar Study Group, MooDS Bipolar Consortium, Walter H, Erk S, Heinz A, Amin N, van Duijn CM, Meyer-Lindenberg A, Tost H, Xiao X, Yamamoto T,* Rietschel M,* Li M.* The Protocadherin 17 Gene Affects Cognition, Personality, Amygdala Structure and Function, Synapse Development and Risk of Major Mood Disorders. Molecular Psychiatry 2017 January 10. doi:10.1038/mp.2016.231.

3.         Chang H,# Li L,# Peng T,# Grigoroiu-Serbanescu M, Bergen SE, Landén M, Hultman CM, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Cichon S, Nöthen MM, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Rietschel M; Swedish Bipolar Study Group; MooDS Consortium, Xiao X,* Li M.* Identification of a Bipolar Disorder Vulnerable Gene CHDH at 3p21.1. Molecular Neurobiology 2017; 54:5166-5176.

4.         Xiao X,# Luo XJ,# Chang H,# Liu Z, Li M.* Evaluation of European Schizophrenia GWAS Loci in Asian Populations via Comprehensive Meta-Analyses. Molecular Neurobiology 2017; 54:4071-4080.

5.         Chang H, Li L, Li M,* Xiao X.* Rare and common variants at 16p11.2 are associated with schizophrenia. Schizophrenia Research 2017; 184:105-108.

6.         Li M, Jaffe AE, Straub RE, Tao R, Shin JH, Wang Y, Chen Q, Li C, Jia Y, Ohi K, Maher BJ, Brandon NJ, Cross A, Chenoweth J, Hoeppner DJ, Wei H, Hyde TM, McKay R, Kleinman JE, Weinberger DR.* A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia associated locus. Nature Medicine 2016; 22:649-656.

7.         Li M,* Chang H, Xiao X. BDNF Val66Met Polymorphism and Bipolar Disorder in European Populations: A Risk Association in Case-Control, Family-based and GWAS Studies. Neuroscience and Biobehavioral Reviews 2016; 68:218-233.

8.         Li M,#,* Wu DD,# Yao YG, Huo YX, Liu JW, Su B, Chasman DI, Chu AY, Huang T, Qi L, Zheng Y, CHARGE Nutrition Working Group, DietGen Consortium, Luo XJ.#,* Recent positive selection drives the expansion of a schizophrenia risk non-synonymous variant at SLC39A8 in Europeans. Schizophrenia Bulletin 2016; 42:178-190.

9.         Li M,#,* Luo XJ,# Landén M, Bergen SE, Hultman CM, Li X, Zhang W, Yao YG, Zhang C, Liu J, Mattheisen M, Cichon S. Mühleisen TW, Degenhardt FA, Nöthen MM, Schulze TG, Grigoroiu-Serbanescu M, Li H, Fuller CK, Chen C, Dong Q, Chen C, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Preisig M, Kutalik Z, Castelao E, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, MooDS Consortium, The Swedish Bipolar Study Group, Rietschel M, Liu C, Kleinman JE, Hyde TM, Weinberger DR, Su B.*Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. British Journal of Psychiatry 2016; 208:128-137.

10.     Li M,#,* Huang L,# Grigoroiu-Serbanescu M,* Bergen SE, Landén M, Hultman CM, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Cichon S, Nöthen MM, Alkelai A, Lerer B, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Rietschel M; MooDS Consortium; Swedish Bipolar Study Group. Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis. Molecular Neurobiology 2016; 53:6608-6619.

11.     Li M,# Luo XJ,# Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Vasquez AA, Hibar DP, Franke B, Martin NG, Wright MJ, MooDS Bipolar Consortium, The Swedish Bipolar Study Group, Alzheimer’ s Disease Neuroimaging Initiative, ENIGMA consortium, CHARGE consortium, Su B.* Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Molecular Psychiatry 2014; 19:452-461.

12.     Luo XJ,#,Li M,# Huang L, Steinberg S, Mattheisen M, Liang G, Donohoe G, Shi Y, Chen C, Yue W, Alkelai A, Lerer B, Li Z, Yi Q, Rietschel M, Cichon S, Collier DA, Tosato S, Suvisaari J, Rujescu D, Golimbet V, Silagadze T, Durmishi N, Milovancevic MP, Stefansson H, Schulze TG, Nöthen MM, Chen C, Lyne R, Morris DW, Gill M, Corvin A, Zhang D, Dong Q, Moyzis RK, Stefansson K, Sigurdsson E, Hu F; MooDS SCZ Consortium, Su B, Gan L.* Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene. Molecular Psychiatry 2014; 19:774-783.

13.     Li M, Ge T, Feng J, Su B.* SLC6A15 rs1545843 and depression: implications from brain imaging data. The American Journal of Psychiatry 2013; 170:805.

14.     Li M, Su B.* Meta-analysis supports association of a non-synonymous SNP in ZNF804A with schizophrenia. Schizophrenia Research 2013; 149:188-189.

15.     Li M,# Luo XJ,# Xiao X,# Shi L, Liu XY, Yin LD, Ma XY, Yang SY, Pu XF, Yu J, Diao HB, Shi H, Su B.* Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population. The World Journal of Biological Psychiatry 2013; 14:91-99.

16.     Li M,# Wang Y,# Zheng XB, Ikeda M, Iwata N, Luo XJ, Chong SA, Lee J, Rietschel M, Zhang FY, Müller-Myhsok B, Cichon S, Weinberger DR, Mattheisen M, Schulze TG, Martin NG, Mitchell PB, Schofield PR, Liu JJ, Su B,* MooDS Consortium. Meta-analysis and brain imaging data support the involvement of VRK2 (rs2312147) in schizophrenia susceptibility. Schizophrenia Research 2012; 142:200-205.

17.     Li M, Luo XJ, Xiao X, Shi L, Liu XY, Yin LD, Diao HB, Su B.* Allelic differences between Han Chinese and Europeans for functional variants in ZNF804A and their association with schizophrenia. The American Journal of Psychiatry 2011; 168:1318-1325.

18.     Li M,# Luo XJ, Zhang X, Yang ZH, Xiang K, Xiao X, Su B,* Zhao YL,# Shen Y, Xu Q,* Chen XN, Chen JC, Liu XY, Yin LD, Ma XY, Yang SY, Yu J, Diao HB, Shi XD. A common variant of the cardiomyopathy associated 5 gene (CMYA5) is associated with schizophrenia in Chinese population.Schizophrenia Research 2011; 129:217-219.

19.     Li M,# Mo Y,# Luo XJ,# Xiao X,# Shi L, Peng YM, Qi XB, Liu XY, Yin LD, Diao HB, Su B.* Genetic association and identification of a functional SNP at GSK3beta for schizophrenia susceptibility. Schizophrenia Research 2011; 133:165-171.

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