Search: 
Home | Contact | Sitemap | 中文 | CAS
  
  About Research Education Partnerships People Resources  
Location: Home > People > Staff
   
LeaderShip
CAS Members
Principal Investigator
Ming Li     
Title
Phone +86 871 65190162;8603
Fax +86 871 65190162
E-mail limingkiz@mail.kiz.ac.cn
Address #32 Jiaochangdong Road, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China
Zip Code 650223
 
   Education and Appointments:
  Professional Services
   Research Interests:
  Supported Projects:

1、中科院昆明动物研究所“百人计划”启动项目 (280万元) 

2、中科院和云南省“动物模型与人类疾病机理”重点实验室项目(50万元) 

  Public Services:
  Honors:
  Selected Publications:

1. Li M, Jaffe AE, Straub RE, Tao R, Shin JH, Wang Y, Chen Q, Li C, Jia Y, Ohi K, Maher BJ, Brandon NJ, Cross A, Chenoweth J, Hoeppner DJ, Wei H, Hyde TM, McKay R, Kleinman JE, Weinberger DR.† A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia associated locus. Nature Medicine 2016; doi:10.1038/nm.4096     

2. Li M,#† Wu DD,# Yao YG, Huo YX, Liu JW, Su B, Chasman DI, Chu AY, Huang T, Qi L, Zheng Y, CHARGE Nutrition Working Group, DietGen Consortium, Luo XJ.#† Recent positive selection drives the expansion of a schizophrenia risk non-synonymous variant at SLC39A8 in Europeans. Schizophrenia Bulletin 2016; 42:178-90.      

3. Li M,#† Luo XJ,# Landén M, Bergen SE, Hultman CM, Li X, Zhang W, Yao YG, Zhang C, Liu J, Mattheisen M, Cichon S. Mühleisen TW, Degenhardt FA, Nöthen MM, Schulze TG, Grigoroiu-Serbanescu M, Li H, Fuller CK, Chen C, Dong Q, Chen C, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Preisig M, Kutalik Z, Castelao E, Wright A, Mitchell PB, Fullerton JM, Schofield PR, Montgomery GW, Medland SE, Gordon SD, Martin NG, MooDS Consortium, The Swedish Bipolar Study Group, Rietschel M, Liu C, Kleinman JE, Hyde TM, Weinberger DR, Su B.† Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance. British Journal of Psychiatry 2016; 208:128-37.  

4. Li M,# Huang L,# Li K,# Huo Y,# Chen C, Wang J, Liu J, Luo Z, Chen C, Dong Q, Yao YG, Su B, Luo XJ.† Adaptive evolution of interleukin-3 (IL3), a gene associated with brain volume variation in general human populations. Human Genetics 2016; 135:377-92.  

5. Li M,# Huang L,# Wang J,# Su B,† Luo XJ.† No association between schizophrenia susceptibility variants and macroscopic structural brain volume variation in healthy subjects. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2016; 171:160-8.  

6. Huang L,# Mo Y,# Sun X, Yu H, Li H, Wu L,† Li M.† The impact of CACNA1C allelic variation on regional gray matter volume in Chinese population. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2016; 171:396-401.  

7. Huang L,# Ohi K,# Chang H, Yu H, Wu L, Yue W, Zhang D, Gao L,† Li M.† A comprehensive meta-analysis of ZNF804A SNPs in the risk of schizophrenia among Asian populations. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2016; 171:437-46.  

8. Yang Z,# Zhong H,# Chen J,# Zhang X,# Zhang H, Luo X, Xu S, Chen H, Lu D, Han Y, Li J, Fu L, Qi X, Peng Y, Xiang K, Lin Q, Guo Y, Li M, Cao X, Zhang Y, Liao S, Peng Y, Zhang L, Guo X, Dong S, Liang F, Wang J, Willden A, Aun HS, Serey B, Sovannary T, Bunnath L, Samnom H, Mardon G, Li Q, Meng A,† Shi H,† Su B.† A genetic mechanism for convergent skin lightening during recent human evolution. Molecular Biology and Evolution 2016 Jan 6. pii: msw003. [Epub ahead of print].  

9. Xiao X,† Li M. Replication of Han Chinese GWAS loci for schizophrenia via meta-analysis of four independent samples. Schizophrenia Research 2016; 172:75-7.  

10. Li M,#† Huang L,# Grigoroiu-Serbanescu M, Bergen SE, Landén M, Hultman CM, Forstner AJ, Strohmaier J, Hecker J, Schulze TG, Müller-Myhsok B, Reif A, Mitchell PB, Martin NG, Cichon S, Nöthen MM, Alkelai A, Lerer B, Jamain S, Leboyer M, Bellivier F, Etain B, Kahn JP, Henry C, Rietschel M; MooDS Consortium; Swedish Bipolar Study Group. Convergent Lines of Evidence Support LRP8 as a Susceptibility Gene for Psychosis. Molecular Neurobiology 2015 Dec 4. [Epub ahead of print]  

11. Liu Z,# Huang L,# Luo XJ, Wu L,† Li M.† MAOA Variants and Genetic Susceptibility to Major Psychiatric Disorders. Molecular Neurobiology 2015 Jul 31. [Epub ahead of print]  

12. Li X,# Zhang W,# Lencz T, Darvasi A, Alkelai A, Lerer B, Jiang HY, Zhang DF, Yu L, Xu XF, Li M,† Yao YG.† Common variants of IRF3 conferring risk of schizophrenia. Journal of Psychiatric Research. 2015; 64:67-73.  

13. Liu J,# Mo Y,# Ge T,# Wang Y, Luo XJ, Feng J, Li M,† Su B.† Allelic variation at 5-HTTLPR is associated with brain morphology in a Chinese population. Psychiatry Research 2015; 266:399-402.  

14. Luo XJ,#† Mattheisen M,# Li M, Huang L, Rietschel M, Børglum AD, Als TD, van den Oord EJ, Aberg KA, Mors O, Mortensen PB, Luo Z, Degenhardt F, Cichon S, Schulze TG, Nöthen MM; iPSYCH-GEMS SCZ working group; MooDS SCZ Consortium, Su B, Zhao Z, Gan L, Yao YG. Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function. Schizophrenia Bulletin 2015; 41:1294-308.  

15. Ohi K, Ursini G, Li M, Shin JH, Ye T, Chen Q, Tao R, Kleinman JE, Hyde TM, Hashimoto R, Weinberger DR.† DEGS2 polymorphism associated with cognition in schizophrenia is associated with gene expression in brain. Translational Psychiatry 2015; 5:e550.  

16. Li M,# Luo XJ,# Rietschel M, Lewis CM, Mattheisen M, Müller-Myhsok B, Jamain S, Leboyer M, Landén M, Thompson PM, Cichon S, Nöthen MM, Schulze TG, Sullivan PF, Bergen SE, Donohoe G, Morris DW, Hargreaves A, Gill M, Corvin A, Hultman C, Toga AW, Shi L, Lin Q, Shi H, Gan L, Meyer-Lindenberg A, Czamara D, Henry C, Etain B, Bis JC, Ikram MA, Fornage M, Debette S, Launer LJ, Seshadri S, Erk S, Walter H, Heinz A, Bellivier F, Stein JL, Medland SE, Vasquez AA, Hibar DP, Franke B, Martin NG, Wright MJ, MooDS Bipolar Consortium, The Swedish Bipolar Study Group, Alzheimer’s Disease Neuroimaging Initiative, ENIGMA consortium, CHARGE consortium, Su B.† Allelic differences between Europeans and Chinese for CREB1 SNPs and their implications in gene expression regulation, hippocampal structure and function, and bipolar disorder susceptibility. Molecular Psychiatry 2014; 19:452-61.   

17. Luo XJ,#† Li M,# Huang L, Steinberg S, Mattheisen M, Liang G, Donohoe G, Shi Y, Chen C, Yue W, Alkelai A, Lerer B, Li Z, Yi Q, Rietschel M, Cichon S, Collier DA, Tosato S, Suvisaari J, Rujescu D, Golimbet V, Silagadze T, Durmishi N, Milovancevic MP, Stefansson H, Schulze TG, Nöthen MM, Chen C, Lyne R, Morris DW, Gill M, Corvin A, Zhang D, Dong Q, Moyzis RK, Stefansson K, Sigurdsson E, Hu F; MooDS SCZ Consortium, Su B, Gan L.† Convergent lines of evidence support CAMKK2 as a schizophrenia susceptibility gene. Molecular Psychiatry 2014; 19:774-83.  

18. Li M,# Ohi K,# Chen C,# He Q, Liu JW, Chen C, Luo XJ, Dong Q,† Hashimoto R,† Su B.† Failure of replicating the association between hippocampal volume and 3 single-nucleotide polymorphisms identified from the European genome-wide association study in Asian populations. Neurobiology of Aging 2014; 35:2883 e1-2.  

19. Luo X,#† Huang L,# Jia P,# Li M, Su B, Zhao Z, Gan L. Protein-protein interaction and pathway analyses of top schizophrenia genes reveal schizophrenia susceptibility genes converge on common molecular networks and enrichment of nucleosome (chromatin) assembly genes in schizophrenia susceptibility loci. Schizophrenia Bulletin 2014; 40:39-49.  

20.Zhang W, Xiao MS, Ji S, Tang J, Xu L, Li X, Li M, Wang HZ, Jiang HY, Zhang DF, Wang J, Zhang S, Xu XF, Yu L, Zheng P, Chen X, Yao YG.† Promoter variant rs2301228 on the neural cell adhesion molecule 1 gene confers risk of schizophrenia in Han Chinese. Schizophrenia Research 2014; 160:88-96.  

21. Yang L,# Zhang R,# Li M, Wu X, Wang J, Huang L, Shi X, Li Q, Su B.† A functional MiR-124 binding-site polymorphism in IQGAP1 affects human cognitive performance. PLOS ONE 2014; 9:e107065.  

22. Li M,† Ge T, Feng J, Su B. SLC6A15 rs1545843 and depression: implications from brain imaging data. The American Journal of Psychiatry 2013; 170:805. 

23. Li M,† Su B. Up-Regulation of NOTCH4 Gene Expression in Bipolar Disorder: Future Studies. The American Journal of Psychiatry 2013; 170:560a-1.  

24. Li M,# Luo XJ,# Xiao X,# Shi L, Liu XY, Yin LD, Ma XY, Yang SY, Pu XF, Yu J, Diao HB, Shi H, Su B.† Analysis of common genetic variants identifies RELN as a risk gene for schizophrenia in Chinese population. The World Journal of Biological Psychiatry 2013; 14:91-9. 

25. Li M, Su B.† Meta-analysis supports association of a non-synonymous SNP in ZNF804A with schizophrenia. Schizophrenia Research 2013; 149:188-9.  

26. Li M,# Zhang H,# Luo XJ, Gao L, Qi XB, Gourraud PA, Su B.† Meta-analysis indicates that the European GWAS-identified risk SNP rs1344706 within ZNF804A is not associated with schizophrenia in Han Chinese population. PLOS ONE 2013; 8:e65780.  

27. Liu J, Numata S, Ikeda M, Watanabe Y, Zheng XB, Luo X, Kinoshita M, Nunokawa A, Someya T, Ohmori T, Bei JX, Chong SA, Lee J, Li Z, Liu J, Iwata N, Shi Y, Li M,† Su B.† An evaluation of association between a novel hippocampal biology related SNP (rs7294919) and schizophrenia. PLOS ONE 2013; 8:e80696.  

28. Li M, Su B.† Impact of the genome-wide schizophrenia risk single nucleotide polymorphism (rs1625579) in miR-137 on brain structures in healthy individuals. Psychiatric Genetics 2013; 23:267.  

29. Xiang K,# Ouzhuluobu,# Peng Y,# Yang Z, Zhang X, Cui C, Zhang H, Li M, Zhang Y, Bianba, Gonggalanzi, Basang, Ciwangsangbu, Wu T, Chen H, Shi H, Qi X,† Su B.† Identification of a Tibetan-specific mutation in the hypoxic gene EGLN1 and its contribution to high-altitude adaptation. Molecular Biology and Evolution 2013; 30:1889-98.  

30. Shi L, Li M, Lin Q, Qi X, Su B.† Functional divergence of the brain-size regulating gene MCPH1 during primate evolution and human origin. BMC Biology 2013; 11:62. 

31. Luo XJ,#† Huang L,# Li M, Gan L.† Protein-protein interaction analysis reveals common molecular processes/pathways that contribute to risk of schizophrenia. Schizophrenia Research 2013; 143:390-2.  

32. Zhang R,# Zhang H,# Li M, Li H, Li Y, Valenzuela RK, Su B, Ma J.† Genetic analysis of common variants in the CMYA5 (cardiomyopathy-associated 5) gene with schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2013; 46:64-9.  

33. Li M,# Wang Y,# Zheng XB, Ikeda M, Iwata N, Luo XJ, Chong SA, Lee J, Rietschel M, Zhang FY, Müller-Myhsok B, Cichon S, Weinberger DR, Mattheisen M, Schulze TG, Martin NG, Mitchell PB, Schofield PR, Liu JJ, Su B,† MooDS Consortium. Meta-analysis and brain imaging data support the involvement of VRK2 in schizophrenia susceptibility. Schizophrenia Research 2012; 142:200-5.  

34. Li M,# Shi CJ,# Shi YY,# Luo XJ, Zheng XB, Li ZQ, Liu JJ, Chong SA, Lee J, Wang Y, Liu XY, Yin LD, Pu XF, Diao HB, Xu Q,† Su B.† ZNF804A and schizophrenia susceptibility in Asian populations. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 2012; 159B:794-802. 

35. Luo XJ,# Li M,# Nho K, Deng M, Chen Q, Weinberger DR, Vasquez AA, Rijpkema M, Mattay VS, Saykin AJ, Shen L, Fernández G, Franke B, Chen JC, Chen XN, Wang JK, Xiao X, Qi XB, Xiang K, Peng YM, Cao XY, Li Y, Shi XD, the Alzheimer’s Disease Neuroimaging Initiative, Gan L,† Su B.† The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors. PLOS ONE 2012; 7:e50375. 

36. Li M, Luo XJ, Xiao X, Shi L, Liu XY, Yin LD, Diao HB, Su B.† Allelic differences between Han Chinese and Europeans for functional variants in ZNF804A and their association with schizophrenia. The American Journal of Psychiatry 2011; 168:1318-25. 

37. Li M,# Mo Y,# Luo XJ,# Xiao X,# Shi L, Peng YM, Qi XB, Liu XY, Yin LD, Diao HB, Su B.† Genetic association and identification of a functional SNP at GSK3b for schizophrenia susceptibility. Schizophrenia Research 2011; 133:165-71.  

38. Li M,# Luo XJ, Zhang X, Yang ZH, Xiang K, Xiao X, Su B,† Zhao YL,# Shen Y, Xu Q,† Chen XN, Chen JC, Liu XY, Yin LD, Ma XY, Yang SY, Yu J, Diao HB, Shi XD. A common variant of the cardiomyopathy associated 5 gene (CMYA5) is associated with schizophrenia in Chinese population. Schizophrenia Research 2011; 129:217-9.  

39. Fang X,# Zhang Y,# Zhang R,# Yang L, Li M, Ye K, Guo X, Wang J,† Su B.† Genome sequence and global sequence variation map with 5.5 million SNPs in Chinese rhesus macaque. Genome Biology 2011; 12:R63.  

40. Zhong H,# Li XL,#† Li M, Hao LX, Chen RW, Xiang K, Qi XB, Ma RZ,† Su B.† Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population. Arthritis Research Therapy 2011; 13:R186.  

41. Shi L, Li M, Su B.† MCPH1/BRIT1 represses transcription of the human telomerase reverse transcriptase gene. Gene 2011; 495:1-9. 

  Research Team:
 
  Home Mail Login Intranet login Living and Working in Kunming
Copyright© Kunming Institute of Zoology Chinese Academy of Sciences .All Rights Reserved
Address:No.32 Jiaochang Donglu Kunming 650223 Yunnan,China
Tel:+86 871 65130513 Fax:+86 871 65191823 【mail】