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Principal Investigator
Xiao-Peng Qi     
Phone +86 871 65110289
Fax +86 871 65110289
Address Kunming Institute of Zoology, Chinese Academy of Sciences Kunming, Yunnan, China 650223
Zip Code 650223
   Education and Appointments:
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  Selected Publications:

1.     Lin Jin*, Xiaomin Guo*, Chuanbin Shen*, Xue Hao*, Peng Sun*, Pengpeng Li, Tao XuChunmiao Hu, Ombati Rose, Hongning Zhou, Mingdong Yang, Cheng-Feng Qin, Jingya Guo, Hua Peng, Mingzhao Zhu, Gong Cheng#, Xiaopeng Qi#, and Ren Lai#. 2018. Salivary factor LTRIN from Aedes aegypti facilitates Zika virus transmission by interfering with the lymphotoxin-b receptor. Nature Immunology, doi:10.1038/s41590-018-0063-9 (IF: 21.506) (#Corresponding author) 

2.     Yang Li*, Xiaomin Guo*, Chunmiao Hu, Yan Du, Chuansheng Guo, Di Wang, Weiheng Zhao, Gonghua Huang, Chunliang Li, Qiumin Lu, Ren Lai#, Tao Xu#, and Xiaopeng Qi#. 2018. Type I IFN operates pyroptosis and necroptosis during multidrug-resistant A. baumannii infection. Cell Death & Differentiation, doi:10.1038/s41418-017-0041-z (IF: 8.339) (#Corresponding author) 

3.     Yan-Hu Liu*, Lu Wang*, Tao Xu*Xiaomin Guo, Yang Li, Ting-Ting Yin, He-Chuan Yang, Yang Hu, Adeniyi C. Adeola, Oscar J. Sanke, Newton O. Otecko, Meng Wang, Yaping Ma, Olaogun S. Charles, Mikkel-Holger S. Sinding, Shyam Gopalakrishnan, José Alfredo Samaniego, Anders J. Hansen, Carlos Fernandes, Philippe Gaubert, Jane Budd, Philip M. Dawuda, Lubin Jiang, M.T.P Gilbert, Weiwei Zhai, Xiaopeng Qi#, Guo-Dong Wang#, Ya-Ping Zhang#. 2018. Whole-genome sequencing of African dogs provides insights into adaptations against tropical parasites. Molecular Biology and Evolution, 35(2): 287-298. (5-Year Impact Factor: 14.558) (#Corresponding author)  

4.     Qiang Shao, Stephanie Herrlinger, Ya-Nan Zhu, Mei Yang, Forrest Goodfellow, Steven L. Stice, Xiaopeng Qi, Melinda A. Brindley, Jian-Fu Chen. 2017. The African Zika virus MR-766 is more virulent and causes more severe brain damage than current Asian lineage and Dengue virus. Development, 144(22): 4114-4124. (IF: 6.059) 

5.     Xiaopeng Qi#. 2016. Formation of membrane pores by gasdermin-N causes pyroptosis.  Sci China Life Sci, 07.26, 59(10): 1071-1073. (#Corresponding author) (IF: 2.781) 

6.     Xiaopeng Qi*, Si Ming Man*, R K Subbarao Malireddi, Rajendra Karki, Christopher Lupfer, Prajwal Gurung, Geoffrey Neale, Clifford Guy, Mohamed Lamkanfi, Thirumala-Devi Kanneganti. 2016. Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infection. The Journal of Experimental Medicine, 213(10): 2081-97. (* Equal Contribution) (IF: 13.912) 

7.     Rajendra Karki,Si Ming Man, Subbarao Malireddi,Sannula Kesavardhana, Qifan Zhu, Amanda R. Burton,Bhesh Raj Sharma, Xiaopeng Qi, Stephane Pelletier, Peter Vogel,  Philip Rosenstiel    & Thirumala-Devi Kanneganti. 2016. NLRC3 is an inhibitory sensor of PI3K–mTOR pathways in cancer. Nature, 540: 583–587. (IF: 38.138) 

8.     Xiaopeng Qi, Prajwal Gurung, R. K. Subbarao Malireddi, Peer W. F.  Karmaus, Deepika Sharma, Peter Vogel, Hongbo Chi, Douglas R. Green and Thirumala-Devi Kanneganti. 2016. Critical role of caspase-8–mediated IL-1 signaling in promoting Th2 responses during asthma pathogenesis. Mucosal Immunology, 10(1): 128-138. (IF: 7.374) 

9.     Yapeng Li, Xiaopeng Qi, Bing Liu, Hua Huang. 2015. The STAT5–GATA2 Pathway Is Critical in Basophil and Mast Cell Differentiation and Maintenance. The Journal of Immunology, 194(9): 4328-38. (IF: 4.92) 

10. Xiaopeng Qi, Jessie Hong, Lee Chaves, Yonghua Zhuang, Yuhong Chen, Demin Wang, Jacob Chabon, Brian Graham, Keitaro Ohmori, Yapeng Li, and Hua Huang. 2013. Antagonistic regulation by the transcription factors C/EBPa and MITF specifies basophil and mast cell fates. Immunity, 39 (1): 97-110. (IF: 24.082) 

11. Zhihong Chen, Shanze Wang, Nkiruka Erekosima, Yapeng Li, Jessie Hong, Xiaopeng Qi, Patricia Merkel, Vijaya Nagabhushanam, Eugene Choo, Rohit Katial, Rafeul Alam, Anita Trikha, HongWei Chu, Yonghua Zhuang, Meiling Jin, Chunxue Bai, and Hua Huang. 2013. IL-4 confers resistance to IL-27-mediated suppression on CD4+ T cells by impairing STAT1 signaling. The Journal of Allergy and Clinical Immunology, 132 (4): 912-921. (IF: 11.48) 

12. Xiaopeng Qi*, Jun Nishida*, Lee Chaves, Keitaro Ohmori and Hua Huang. 2011. C/EBPα is critical for interleukin-4 expression in response to FcεR1 receptor cross-linking. The Journal of Biological Chemistry, 286 (18): 16063-16073. (* Equal Contribution)  

13. Xiaopeng Qi, Tyler Droste and Cheng Kao. 2011. Cell-Penetrating Peptides Derived from Viral Capsid Proteins. Molecular Plant-Microbe Interactions. 24 (1): 25-36. 

14. Xiaopeng Qi, Forrest Sheng Bao and Zhixin Xie. 2009. Small RNA Deep Sequencing Reveals Role for Arabidopsis thaliana RNA-dependent RNA polymerases in Viral siRNA Biogenesis. PLoS one, 4 (3):e4971.

15. Xiaopeng Qi, Zhongchang Wu, Jinhui Li, Xiaorong Mo, Shihua Wu, Jun Chu, Ping Wu. 2007. AtCYT-INV1, a neutral invertase, is involved in osmotic stress-induced inhibition on lateral root growth in Arabidopsis. Plant Molecular Biology, 64: 575-587.

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