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Principal Investigator
Dong-Dong Wu     
Phone +86 871 68526518
Zip Code 650223
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  Selected Publications:

1. Wu DD#, Ding XD, Wang S, Wójcik JM, Zhang Y, Tokarska M, Li Y, Wang MS, Faruque O, Nielsen R#, Zhang Q#, Zhang YP#. Pervasive introgression facilitated domestication and adaptation in the Bos species complex. Nature Ecol Evol. 2018 2(7):1139-1145.

2. Zeng L, Ming C, …, Wu DD# Zhang YP #. Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing. Molecular Biology and Evolution 22018 1:149–158. (cover)

3. Zeng L, Ming C, …, Wu DD, # and Zhang YP #. Rapid Evolution of Genes Involved in Learning and Energy Metabolism for Domestication of the Laboratory Rat. Molecular Biology and Evolution 2017, 34(12):3148-3153.

4.  Li Y, Wang MS, Otecko N, Wang W, Shi P, Wu DD#, Zhang YP#. Hypoxia Potentially Promotes Tibetan Longevity. Cell Research 2017 27(2):302-305.

5. Wang MS, Yang HC, Otecko N, Wu DD#, Zhang YP#. Olfactory genes in Tibetan wild boar. Nature Genetics 2016 48(9):972-973.

6.  Wang MS, Su LY, Li Y, Peng MS, Liu HQ, Zeng L, Irwin DM, Yao YG, Wu DD*, and Zhang YP *. Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication. Cell Research 2016 26(5):556-573

7.  Wang MS*, Li Y*, Peng MS*, Zhong L, Wang ZJ, Li QY, Tu XL, Dong Y, Zhu CL, Wang L, Yang MM, Wu SF, Miao YW, Liu JP, Irwin DM, Wang W, Wu DD#, Zhang YP#. Genomic Analyses Reveal Potential Independent Adaptation to High Altitude in Tibetan Chickens.  Molecular Biology and Evolution 2015 32(7):1880-1889.

8. Li Y, Wu DD #, Boyko AR, Wang GD, Wu SF, Irwin DM, Zhang YP#. Population variation revealed high-altitude adaptation of Tibetan mastiffs.  Molecular Biology and Evolution 2014 31(5):1200-1205. 

9. Li Y, vonHoldt BM, Reynolds A, Boyko AR, Wayne RK, Wu DD#, Zhang YP#. Artificial selection on brain expressed genes during the domestication of dog. Molecular Biology and Evolution 2013 30(8):1867-76. 

10. Jin W*, Wu DD*#, Zhang X, Irwin DM, Zhang YP#. Positive Selection on the Gene RNASEL: Correlation between Patterns of Evolution and Function. Molecular Biology and Evolution 2012 29(10):3161-8.

11. Wu DD, Irwin DM, Zhang YP. De novo origin of human protein coding genes. PLoS Genetics 2011 7(11):e1002379

12. Wu DD, Wang GD, Irwin DM, Zhang YP. A profound role for the expansion of trypsin-like serine protease family in the evolution of hematophagy in mosquito. Molecular Biology and Evolution 2009 26(10):2333-2341

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